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12th EuroBiotechnology Congress

Alicante, Spain

Magdalena Zuk

Magdalena Zuk

Wroclaw University, Poland

Title: Chalcone synthase regulates flax metabolism and positively diversify linseed products


Biography: Magdalena Zuk


The chalcone synthase (CHS) gene controls the first step in the flavonoid biosynthesis route, the metabolic pathway in which anthocyanins, phenolic acids, lignins, simply phenols were produced. The transgenic plants with overexpression of the heterological CHS gene were generated, leading to the increased synthesis of flavonoids, high antioxidant potential and improve the properties of products obtained such as flax fiber and oil. At the same time, repressing the endogenous CHS gene should verify the results of research on its overexpression and provide information on its potential role of CHS in the redistribution of substrates and diversification of metabolites within the phenylpropanoid pathway, especially in relation to lignins. In flax, CHS down-regulation resulted in tannin accumulation and reduction in lignin synthesis but plant growth was not affected. This suggests that lignin content and thus cell wall characteristics might be modulated through chalcone synthase gene activity. The important role of CHS gene is in regulation of cell wall sensing as well as polymer content and arrangement. CHS-reduced flax also showed significant changes in morphology and arrangement of the cell wall. The additional result of this work was indication of relationship between the expression of the CHS gene and the metabolism and stability of fatty acid in flax. Plant with reduction of CHS produced oil with ideal proportion of ω6/ω3 fatty acids. Summing up CHS modification induces signal transduction cascade that leads to modification of flax metabolism in a wide range and positively diversify its products