Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 12th EuroBiotechnology Congress Alicante, Spain.

Day 1 :

Keynote Forum

Stefan Selbert

PolyGene Transgenetics, Switzerland

Keynote: State-of-the-art technologies for the generation of animal models of human disease

Time : 09:00

OMICS International Euro Biotechnology 2016 International Conference Keynote Speaker Stefan Selbert photo
Biography:

Stefan Selbert has achieved his PhD at the Max-Planck-Institute of Biochemistry in Martinsried and holds a certificate in Business Administration. He also functions as an Evaluator in Brussels for EU-FP7-PEOPLE and EUREKA Eurostar programs

Abstract:

Animal models play a critical role in the exploration and characterization of disease pathophysiology, target identification and in the in vivo evaluation of novel therapeutic agents and treatments. The “better” the animal model, the higher the chances that clinical trials will be successful and drugs will enter the market at lower costs, in shorter time. Genome engineering technologies have soared in recent years: Chemical mutagenesis, RNA interference, gene targeting in ES-cells, humanized genes and most recently nucleases, such as ZFNs, TALENs and CRISPR/Cas9. New technologies provide new avenues not only to mimic multi factor based disease such as cancer but also to extend model generation on higher species and even human or patient derived cells and tissue. New inducible switches are underway which will allow altering gene expression of not just one but multiple genes and even entire signal transduction pathways within the same cell and tissue, e.g., during disease progression at will in a temporospatial control way. Technologies presented will be of tremendous value for future generations of cellular or animal models and when carefully selected, designed and conducted will play an important part of any translational drug development strategy

Keynote Forum

Denis SPITZER

French-German Research Institute of Saint-Louis, France

Keynote: Large-scale continuous manufacturing of nano-cocrystal drugs and therapeutics

Time : 09:40

OMICS International Euro Biotechnology 2016 International Conference Keynote Speaker Denis SPITZER photo
Biography:

Denis SPITZER received his PhD in physical chemistry in 1993 at the University Louis Pasteur of Strasbourg. He is the founding and current Director of the NS3E Research Laboratory UMR 3208 ISL/CNRS/UNISTRA. He conducts research in continuous nanoscristallization processes of organic nanomaterials such as model medicaments and energetic materials. He is the inventor of the SFE process.  He is the author of more than 150 publications and scientific reports. He received in 2013 the award of strategic thinking given by the French Homeland Minister, and more recently, in 2015, the « Grand Prix Lazare Carnot » award of the French Academy of Science, for dual use research

Abstract:

NS3E laboratory developed the Spray Flash Evaporation (SFE) for preparing energetic organic nanoparticles at industrial scale. The energetic solution is kept in a pressurized tank separated from a vacuum chamber by a hollow cone nozzle, used both to heat and spray the liquid. The instantaneous evaporation of the solvent originates from the combination of the abrupt pressure drop and the high energy stored by the overheated solvent prior to nebulization. The flash evaporation leads to small crystallites with narrow size distribution. The nanoparticles may be composed of single compounds, mixtures of several substances or co-crystals. The idea to transport these findings to the medicine became evident. In this domain, co-crystals are of critical importance as they enhance bioavailability and up-take by the human body of Active Pharmaceutical Ingredients (API). Up to now, most used techniques are of batch nature and not able to give access in big amounts to nanosized crystals or co-crystals of therapeutic interest. The SFE permits the continuous manufacturing of nanosized co-crystals, in large amounts with a kinetic complying with the pharmaceutical industry’s requirements. The efficiency of SFE was shown by the manufacturing of nano-cocrystals based on caffeine/oxalic acid (2/1) and caffeine/glutaric acid (1/1) with a mean particle size of 60 and 100 nanometers respectively. SFE currently used to produce nano-cocrystals, offers other promising prospects at the interplay between medicine and energetics that will be highlighted in this conference.

Keynote Forum

Thomas McKeon

United States Department of Agriculture, USA

Keynote: Industrial oil crops as renewable resources providing replacements for petrochemicals

Time : 10:20

OMICS International Euro Biotechnology 2016 International Conference Keynote Speaker Thomas McKeon photo
Biography:

Thomas McKeon has received his PhD in Biochemistry at UC Berkeley and Postdoctoral research in Plant Biochemistry at UC Davis. He has over 100 publications, mostly in plant lipid enzymology and molecular biology. He is an Editor and chapter author for the book Industrial Oil Crops, published in March, 2016 by Elsevier and AOCS Press. He is an Editor for Biocatalysis and Agricultural Biotechnology (BAB), Board Member for American Oil Chemists Society (AOCS), Biotechnology Division and International Society for Biocatalysis and Agricultural Biotechnology (ISBAB). He has organized conferences for ISBAB and for US-Japan Natural Resources (UJNR) Food and Agriculture Panel

Abstract:

Thomas McKeon has received his PhD in Biochemistry at UC Berkeley and Postdoctoral research in Plant Biochemistry at UC Davis. He has over 100 publications, mostly in plant lipid enzymology and molecular biology. He is an Editor and chapter author for the book Industrial Oil Crops, published in March, 2016 by Elsevier and AOCS Press. He is an Editor for Biocatalysis and Agricultural Biotechnology (BAB), Board Member for American Oil Chemists Society (AOCS), Biotechnology Division and International Society for Biocatalysis and Agricultural Biotechnology (ISBAB). He has organized conferences for ISBAB and for US-Japan Natural Resources (UJNR) Food and Agriculture Panel