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Georgios Skretas

Georgios Skretas

Research Assistant Professor
National technical University of Athens
Greece

Biography

Georgios Skretas graduated from the School of Chemical Engineering of the National technical University of Athens (Greece) in 1998 and received his PhD in Chemical Engineering from Princeton University (USA) in 2006. He then moved on to the University of Texas at Austin (USA) to carry out post-doctoral research training under the guidance of Prof. George Georgiou. Since 2009, Dr. Skretas has been the principal investigator of the Laboratory of Enzyme & Synthetic Biotechnology at the Institute of Biology, Medicinal Chemistry & Biotechnology of the National Hellenic Research Foundation (Greece), where he currently holds the rank of Research Assistant Professor.

Research Interest

Protein misfolding and aggregation. Molecular evolution of compounds with potentially therapeutic effects against protein misfolding diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis, and certain forms of cancer. Development of novel protein-based tools for applications in synthetic biology. Production of hard-to-express recombinant proteins, such as human integral membrane proteins, in microbial cells. Discovery of thermostable hydrolytic enzymes of industrial interest using metagenomic approaches and directed protein evolution. Development of biosensors of protein conformations and dynamics.